Centriolin 抗体 (C-Term)
Quick Overview for Centriolin 抗体 (C-Term) (ABIN7226084)
抗原
See all Centriolin (CNTRL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Centriolin Polyclonal Antibody
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特异性
- Centriolin Polyclonal Antibody detects endogenous levels of Centriolin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Centriolin
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Centriolin (CNTRL)
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别名
- Centriolin
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背景
- Rabbit Anti-Centriolin Polyclonal Antibody,CCP110, CEP110, CP110, KIAA0419, Centriolar coiled-coil protein of 110 kDa, Centrosomal protein of 110 kDa, CP110, Cep110,Cytokinesis occurs during the late stages of mitosis and describes the process by which the cytoplasm of one cell is divided to create two subsequent daughter cells. Centriolin, also known as CEP110, is a coiled-coil centrosomal protein that is required for centrosome maturation and correct centrosome function. During abscission, the last step in cytokinesis, Centriolin both coordinates and grounds vesicle-fusion and vesicle-exocyst complexes to the midbody of the daughter cells. Acting as an anchor for the protein complexes needed to complete separation of the two cells, Centriolin initiates and controls vesicle-mediated cell cleavage. Through its ability to signal initiation of the last step of vertebrate cytokinesis, Centriolin regulates cell proliferation and contributes to proper entry into the S phase of mitosis.,Centriolar coiled-coil protein of 110 kDa
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基因ID
- 9738
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UniProt
- O43303
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途径
- M Phase, SARS-CoV-2 Protein Interactome
抗原
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