Centriolin 抗体 (AA 850-900)
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北京 101111
Quick Overview for Centriolin 抗体 (AA 850-900) (ABIN1451145)
抗原
See all Centriolin (CNTRL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 850-900
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原理
- Centriolin Antibody
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特异性
- Centriolin Polyclonal Antibody detects endogenous levels of Centriolin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CEP110. AA range:850-900
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Centriolin (CNTRL)
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别名
- CEP110
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背景
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Synonyms: CCP110, CEP110, CP110, KIAA0419, Centriolar coiled-coil protein of 110 kDa, Centrosomal protein of 110 kDa, CP110, Cep110
Background: function:Necessary for centrosome duplication. Collaborates with CEP97, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.,induction:Up-regulated during the transition from G1 to S phase of the cell cycle. The highest levels are observed in S phase, after which the levels decrease markedly.,PTM:Phosphorylated by CDKs.,subunit:Interacts with CALM1, CETN2 and CEP97.,tissue specificity:Highly expressed in testis. Detected at intermediate levels in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.,
Gene Name: CCP110
Protein Name: Centriolar coiled-coil protein of 110 kDa
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分子量
- 113 kDa
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基因ID
- 9738
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OMIM
- 609544
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UniProt
- O43303
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途径
- M Phase, SARS-CoV-2 Protein Interactome
抗原
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