Centriolin 抗体 (C-Term)
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北京 101111
Quick Overview for Centriolin 抗体 (C-Term) (ABIN6260763)
抗原
See all Centriolin (CNTRL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- CEP110 Antibody
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特异性
- CEP110 Antibody detects endogenous levels of total CEP110
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CEP110, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Centriolin (CNTRL) (AA 2101-2325) antibody
CNTRL 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centriolin (CNTRL) (C-Term) antibodyCNTRL 适用: 人, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centriolin (CNTRL) (C-Term) antibodyCNTRL 适用: 人, 小鼠, 大鼠 WB, IF, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200 IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Centriolin (CNTRL)
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别名
- CEP110
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背景
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Description: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Gene: CCP110
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分子量
- 113kDa
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基因ID
- 9738
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UniProt
- O43303
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途径
- M Phase, SARS-CoV-2 Protein Interactome
抗原
-
