CDC45 抗体 (AA 90-170)
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Quick Overview for CDC45 抗体 (AA 90-170) (ABIN7227774)
抗原
See all CDC45 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-170
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原理
- CDC45 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of CDC45 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human CDC45 protein at AA range: 90-170
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
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别名
- CDC45
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背景
- Rabbit Anti-CDC45 Polyclonal Antibody,Cell division control protein 45 homolog, PORC-PI-1,The protein encoded by CDC45 was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.,CDC45
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分子量
- observerd band 62kDa
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基因ID
- 8318
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UniProt
- O75419
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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