CDC25B 抗体
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北京 101111
Quick Overview for CDC25B 抗体 (ABIN7226172)
抗原
See all CDC25B 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Cdc25B Polyclonal Antibody
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特异性
- Cdc25B Polyclonal Antibody detects endogenous levels of Cdc25B protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Cdc25B around the non-phosphorylation site of S323
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
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别名
- Cdc25B
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背景
- Rabbit Anti-Cdc25B Polyclonal Antibody,CDC25B, CDC25HU2, M-phase inducer phosphatase 2, Dual specificity phosphatase Cdc25B,CDC25B (cell division cycle 25B) is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.,M-phase inducer phosphatase 2
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分子量
- observerd band 65kDa
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基因ID
- 994
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UniProt
- P30305
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途径
- Cell Division Cycle, M Phase, Autophagy
抗原
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