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CD70 抗体 (AA 150-193)

The 兔 多克隆 anti-CD70 antibody is suitable to detect CD70 in samples from 人 和 小鼠. It has been validated for ELISA, IHC 和 IF.
产品编号 ABIN7227764
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD70 抗体 (AA 150-193) (ABIN7227764)

抗原

See all CD70 抗体
CD70 (CD70 Molecule (CD70))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CD70 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 150-193

    原理

    Rabbit Anti-CD70 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CD70

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human CD70 protein at AA range: 150-193

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CD70 (CD70 Molecule (CD70))

    别名

    CD70

    背景

    CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD antigen CD70The protein encoded by CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Akt Signaling. is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Akt Signaling.

    基因ID

    970

    UniProt

    P32970

    途径

    Cancer Immune Checkpoints
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