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CD5 抗体

This anti-CD5 antibody is a 兔 多克隆 antibody detecting CD5 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7214074
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD5 抗体 (ABIN7214074)

抗原

See all CD5 抗体
CD5

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    CD5 Polyclonal Antibody

    特异性

    CD5 Polyclonal Antibody detects endogenous levels of CD5 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human CD5 around the non-phosphorylation site of Y453

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CD5

    别名

    CD5

    背景

    Rabbit Anti-CD5 Polyclonal Antibody,CD5, LEU1, T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD antigen CD5,CD5 (also designated Lyt-1) has been identified as a transmembrane glycoprotein that is expressed on 70 % of normal peripheral blood lymphocytes and on virtually all T lymphocytes in thymus and peripheral blood. Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5, and the absence of CD5 renders T cells hyper-responsive to TCR-mediated activation. CD5 associates with the TCR/ CD3-z chain and with the Src family kinase Lck p56. In vitro studies have shown a 10- to 15-fold increase in the kinase activity of Lck bound to CD5. The B cell antigen, CD72, serves as a receptor for CD5. The consequence of CD5 binding to its cognate receptor is still in question and likely plays a role in thymic selection.,T-cell surface glycoprotein CD5

    分子量

    observerd band 60kDa

    基因ID

    921

    UniProt

    P06127
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