CD5 抗体
Our Local Distributor
北京 101111
Quick Overview for CD5 抗体 (ABIN7211956)
抗原
See all CD5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- CD5 Monoclonal Antibody
-
特异性
- The antibody detects endogenous CD5 proteins.
-
纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
-
免疫原
- Synthetic Peptide
-
亚型
- IgG1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:100-1:200), IHC-P (1:200).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- CD5
-
别名
- CD5
-
背景
- Mouse Anti-CD5 Monoclonal Antibody,CD5, LEU1, T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5,CD5 (also designated Lyt-1) has been identified as a transmembrane glycoprotein that is expressed on 70 % of normal peripheral blood lymphocytes and on virtually all T lymphocytes in thymus and peripheral blood. Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5, and the absence of CD5 renders T cells hyper-responsive to TCR-mediated activation. CD5 associates with the TCR/ CD3-z chain and with the Src family kinase Lck p56. In vitro studies have shown a 10- to 15-fold increase in the kinase activity of Lck bound to CD5. The B cell antigen, CD72, serves as a receptor for CD5. The consequence of CD5 binding to its cognate receptor is still in question and likely plays a role in thymic selection.,T-cell surface glycoprotein CD5
-
基因ID
- 921
-
UniProt
- P06127
抗原
-