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CD3 epsilon 抗体 (Internal Region)

The 兔 多克隆 anti-CD3 epsilon antibody (ABIN7225850) specifically detects CD3 epsilon in WB, IHC, IF 和 ELISA. The antibody is reactive with 人, 小鼠, 大鼠 和 猴 samples.
产品编号 ABIN7225850
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD3 epsilon 抗体 (Internal Region) (ABIN7225850)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

适用

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人, 小鼠, 大鼠, 猴

宿主

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  • 11
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  • 2
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克隆类型

  • 504
  • 141
  • 8
  • 3
多克隆

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

  • 400
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 79
    • 41
    • 27
    • 20
    • 20
    • 16
    • 16
    • 14
    • 12
    • 12
    • 9
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    • 6
    • 4
    • 4
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    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    Internal Region

    原理

    Rabbit Anti-CD3-ε Polyclonal Antibody

    特异性

    CD3-ε Polyclonal Antibody detects endogenous levels of CD3-ε protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from the Internal region of human CD3-epsilon

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3-epsilon

    背景

    CD3E, T3E, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD antigen CD3eThe protein encoded by CD3E (CD3e molecule) is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in CD3E cause immunodeficiency. CD3E has also been linked to a susceptibility to type I diabetes in women.

    分子量

    21kD

    基因ID

    916

    UniProt

    P07766

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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