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PD-L1 抗体 (AA 181-230)

This anti-PD-L1 antibody is a 兔 多克隆 antibody detecting PD-L1 in ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN7227724
发货至: 中国

Quick Overview for PD-L1 抗体 (AA 181-230) (ABIN7227724)

抗原

See all PD-L1 抗体
PD-L1 (CD274 (PD-L1))

适用

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宿主

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克隆类型

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多克隆

标记

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This PD-L1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 181-230

    原理

    CD274 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of CD274

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human CD274 protein at AA range: 181-230

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    CD274

    背景

    Rabbit Anti-CD274 Polyclonal Antibody,Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD antigen CD274,CD274, also commonly referred to as PDL1, is a ligand that binds with the receptor PD1, commonly found on T-cells, and acts to block T-cell activation. PD1 expression has been observed in a variety of cancers including melanoma and non-small cell lung cancer. The interaction of PD1/PDL1 is hypothesized to be a possible mechanism for the tumor to escape immune response. A number of checkpoint blockade inhibitors including pembrolizumab and nivolumab have been developed that target the PD1/PDL1 interaction in order to allow T-cells to recognize tumor cells without being deactivated by the tumor.,CD274

    基因ID

    29126

    UniProt

    Q9NZQ7

    途径

    Cancer Immune Checkpoints
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