DC-SIGN/CD209 抗体 (Internal Region)
Quick Overview for DC-SIGN/CD209 抗体 (Internal Region) (ABIN7218768)
抗原
See all DC-SIGN/CD209 (CD209) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- CD209 Polyclonal Antibody
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特异性
- CD209 Polyclonal Antibody detects endogenous levels of CD209 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human CD209
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亚型
- IgG
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anti-CD209 (CD209) (AA 70-404) antibody
CD209 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC, FACS, IF, ISt, StM 宿主: 小鼠 Monoclonal C209-1781 unconjugated
anti-CD209 (CD209) (AA 270-404) antibodyCD209 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5C2A6 unconjugated
anti-CD209 (CD209) (AA 297-380) antibodyCD209 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-CD209 (CD209) (AA 1-404) antibodyCD209 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 IHC, FACS, IHC (p), IP 宿主: 大鼠 Monoclonal h209 unconjugated
anti-CD209 (CD209) (AA 115-238) antibodyCD209 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) (AA 265-404) antibodyCD209 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) (AA 271-380) antibodyCD209 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 3B10 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DC-SIGN/CD209 (CD209) (CD209)
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别名
- CD209
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背景
- Rabbit Anti-CD209 Polyclonal Antibody,CD209, CLEC4L, CD209 antigen, C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CD209,CD209 encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The CD209 Molecule is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332, often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.,CD209 antigen
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分子量
- observerd band 45kDa
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基因ID
- 30835
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UniProt
- Q9NNX6
抗原
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