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beta Catenin 抗体 (pThr41)

This 兔 多克隆 anti-beta Catenin antibody specifically detects beta Catenin in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7212900
发货至: 中国
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Quick Overview for beta Catenin 抗体 (pThr41) (ABIN7212900)

抗原

See all beta Catenin (CATNB) 抗体
beta Catenin (CATNB) (Catenin, beta (CATNB))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This beta Catenin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pThr41

    原理

    Catenin-β (phospho Thr41/S45) Polyclonal Antibody

    特异性

    Phospho-Catenin-β (T41/S45) Polyclonal Antibody detects endogenous levels of Catenin-β protein only when phosphorylated at T41/S45.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Catenin-beta Phospho-Thr41/S45

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    别名

    Catenin-beta

    背景

    Rabbit Anti-Catenin-β (phospho Thr41/S45) Polyclonal Antibody,CTNNB1, CTNNB, OK/SW-cl.35, Catenin beta-1, Beta-catenin,Catenin beta 1 encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Catenin beta 1 also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, catenin beta 1 binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.,Catenin beta-1

    分子量

    observerd band 85kDa

    基因ID

    1499

    UniProt

    P35222

    途径

    Peptide Hormone Metabolism
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