Caspase 5 p20 抗体 (Cleaved-Asp121)
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Quick Overview for Caspase 5 p20 抗体 (Cleaved-Asp121) (ABIN7212444)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-160, Cleaved-Asp121
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原理
- Cleaved-Caspase-5 p20 (D121) Polyclonal Antibody
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特异性
- Cleaved-Caspase-5 p20 (D121) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-5 p20 protein resulting from cleavage adjacent to D121.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Caspase-5 p20 at AA range: 80-160
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亚型
- IgG
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anti-Caspase 5 p20 (Asp121), (cleaved) antibody
适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5 p20 (Cleaved-Asp121) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5 p20 (Center) antibody适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Caspase 5 p20
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别名
- Caspase-5 p20
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背景
- Rabbit Anti-Cleaved-Caspase-5 p20 (D121) Polyclonal Antibody,CASP5, ICH3, Caspase-5, CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY,CASP5 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of caspase 5 induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by caspase 5, this process requires Fas-mediated dephosphorylation of Max. The expression of CASP5 is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for CASP5.,Caspase-5
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分子量
- observerd band 22kDa
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基因ID
- 838
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UniProt
- P51878
抗原
-
