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Caspase 5 p20 抗体 (Cleaved-Asp121)

适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5955946
发货至: 中国
  • 抗原 See all Caspase 5 p20 products
    Caspase 5 p20
    抗原表位
    • 1
    • 1
    • 1
    Cleaved-Asp121
    适用
    • 2
    • 1
    • 1
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This Caspase 5 p20 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA
    特异性
    Apoptosis related cysteine protease,CASP-5,CASP5,CASP5,Caspase-5 subunit p10,ICE(rel)-III,ICERELIII,ICH 3,ICH 3 protease,Protease ICH-3,Protease TY,TY,TY protease
    纯化方法
    Affinity purification
    免疫原
    Synthesized peptide derived from the Internal region of human Caspase-5 p20
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, ELISA 1:20000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Caspase 5 p20
    别名
    Caspase-5 p20 (Caspase 5 p20 产品)
    背景
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
    分子量
    48kDa
    基因ID
    838
    UniProt
    P51878
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