Caspase 3 p17 (AA 100-180), (Cleaved-Asp175) 抗体
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Quick Overview for Caspase 3 p17 (AA 100-180), (Cleaved-Asp175) 抗体 (ABIN7202045)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-180, Cleaved-Asp175
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原理
- Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody
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特异性
- Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-3 p17 protein resulting from cleavage adjacent to D175.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Caspase-3 p17 at AA range: 100-180
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亚型
- IgG
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anti-Caspase 3 p17 (Cleaved-Asp175) antibody
适用: 人, 小鼠, 大鼠 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 p17 (Asp175), (cleaved) antibody适用: 人, 小鼠, 大鼠 WB, IF, IHC (pfa) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 p17 (Center) antibody适用: 人, 小鼠, 大鼠, Cow, 猴, 绵羊 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 p17 (Center) antibody适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:50-1:300), IHC-P (1:50-1:300), ELISA (1:20000). Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Caspase 3 p17
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别名
- Caspase-3 p17
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背景
- Rabbit Anti-Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody,CASP3, CPP32, Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1,CASP3 encodes caspase 3 which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 3 cleaves and activates caspases 6, 7 and 9, and caspase 3 itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of CASP3 results in two transcript variants that encode the same protein.,Caspase-3
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基因ID
- 836
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UniProt
- P42574
抗原
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