Caspase 3 p17 (Cleaved-Asp175) 抗体
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- 抗原
- Caspase 3 p17
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抗原表位
- Cleaved-Asp175
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Synthesized peptide derived from the Internal region of human Caspase-3 p17
- 亚型
- IgG
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anti-Caspase 3 p17 (AA 100-180), (Cleaved-Asp175) antibody
适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 p17 (Asp175), (cleaved) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 p17 (Center) antibody适用: 人, 小鼠, 大鼠, Cow, 猴, 绵羊 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 p17 (Center) antibody适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Caspase 3 p17
- 别名
- CASP3 p17
- 背景
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
- 分子量
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Observed_MW: 20 kDa
Calculated_MW: 32 kDa
- UniProt
- P42574
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