Casein Kinase 1 gamma 2 抗体 (AA 10-90)
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Quick Overview for Casein Kinase 1 gamma 2 抗体 (AA 10-90) (ABIN7219762)
抗原
See all Casein Kinase 1 gamma 2 (CSNK1G2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- Casein Kinase Iγ2 Polyclonal Antibody
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特异性
- Casein Kinase Iγ2 Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human Casein Kinase Igamma2 at AA range: 10-90
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亚型
- IgG
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anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 316-415), (Isoform gamma) antibody
CSNK1G2 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 1-415) antibodyCSNK1G2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 315-415) antibodyCSNK1G2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (C-Term) antibodyCSNK1G2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 1-415) antibodyCSNK1G2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 1-415) antibodyCSNK1G2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F4 unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) antibodyCSNK1G2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (N-Term) antibodyCSNK1G2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 130-179) antibodyCSNK1G2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, gamma 2 (CSNK1G2) (AA 170-415) antibodyCSNK1G2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
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别名
- Casein Kinase Igamma2
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背景
- Rabbit Anti-Casein Kinase Iγ2 Polyclonal Antibody,CSNK1G2, CK1G2, Casein kinase I isoform gamma-2, CKI-gamma 2,Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis.,Casein kinase I isoform gamma-2
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分子量
- observerd band 47kDa
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基因ID
- 1455
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UniProt
- P78368
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途径
- Hedgehog Signaling
抗原
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