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CaMKIIalpha/delta 抗体

This anti-CaMKIIalpha/delta antibody is a 兔 多克隆 antibody detecting CaMKIIalpha/delta in IF, WB, IHC (p) 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7225196
发货至: 中国

Quick Overview for CaMKIIalpha/delta 抗体 (ABIN7225196)

抗原

CaMKIIalpha/delta

适用

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人, 小鼠, 大鼠

宿主

  • 7

克隆类型

  • 7
多克隆

标记

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This CaMKIIalpha/delta antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
  • 原理

    CaMKIIα/δ Polyclonal Antibody

    特异性

    CaMKIIα/δ Polyclonal Antibody detects endogenous levels of CaMKIIα/δ protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human CaMKIIalpha/delta around the non-phosphorylation site of T286

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    CaMKIIalpha/delta

    背景

    Rabbit Anti-CaMKIIα/δ Polyclonal Antibody,CAMK2A, CAMKA, KIAA0968, Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2D, CAMKD, Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II,The product of CAMK2A (calcium/calmodulin dependent protein kinase II alpha) belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for CAMK2A.,Calcium calmodulin-dependent protein kinase type II subunit alpha delta

    分子量

    observerd band 54kDa

    基因ID

    815, 817
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