Cadherin 8 抗体 (AA 460-540)
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Quick Overview for Cadherin 8 抗体 (AA 460-540) (ABIN7218878)
抗原
See all Cadherin 8 (CDH8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 460-540
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原理
- Cadherin-8 Polyclonal Antibody
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特异性
- Cadherin-8 Polyclonal Antibody detects endogenous levels of Cadherin-8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Cadherin-8 at AA range: 460-540
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cadherin 8 (CDH8)
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别名
- Cadherin-8
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背景
- Rabbit Anti-Cadherin-8 Polyclonal Antibody,CDH8, Cadherin-8,CDH8 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.,Cadherin-8
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分子量
- observerd band 90kDa
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基因ID
- 1006
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UniProt
- P55286
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途径
- Cell-Cell Junction Organization
抗原
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