Cadherin 8 抗体 (AA 491-540)
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Quick Overview for Cadherin 8 抗体 (AA 491-540) (ABIN1534298)
抗原
See all Cadherin 8 (CDH8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 491-540
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原理
- Cadherin-8 Antibody
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特异性
- Cadherin-8 Polyclonal Antibody detects endogenous levels of Cadherin-8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human CDH8. AA range:491-540
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cadherin 8 (CDH8)
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别名
- CDH8
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背景
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Synonyms: CDH8; Cadherin-8
Background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008],
Gene Name: CDH8
Protein Name: Cadherin-8
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分子量
- 88 kDa
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基因ID
- 1006
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OMIM
- 603008
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UniProt
- P55286
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途径
- Cell-Cell Junction Organization
抗原
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