Cadherin 5 抗体 (pTyr731)
Quick Overview for Cadherin 5 抗体 (pTyr731) (ABIN7218860)
抗原
See all Cadherin 5 (CDH5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr731
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原理
- VE-Cadherin (phospho Tyr731) Polyclonal Antibody
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特异性
- Phospho-VE-Cadherin (Y731) Polyclonal Antibody detects endogenous levels of VE-Cadherin protein only when phosphorylated at Y731.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human VE-Cadherin Phospho-Tyr731
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亚型
- IgG
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anti-Cadherin 5 (CDH5) (AA 601-700) antibody
CDH5 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (Internal Region) antibodyCDH5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 68-307) antibodyCDH5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 650-750) antibodyCDH5 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 29-223) antibodyCDH5 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3D5C7 unconjugated
anti-Cadherin 5 (CDH5) (AA 29-223) antibodyCDH5 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3D5C7 unconjugated
anti-Cadherin 5 (CDH5) (C-Term) antibodyCDH5 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 766-784) antibodyCDH5 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 251-320) antibodyCDH5 适用: 人, 小鼠 FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 59-382) antibodyCDH5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cadherin 5 (CDH5)
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别名
- VE-Cadherin
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背景
- Rabbit Anti-VE-Cadherin (phospho Tyr731) Polyclonal Antibody,CDH5, Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin, CD antigen CD144,Vascular endothelial (VE)-cadherin (VE-CAD), also called 7B4 and cadherin-5 (CDH5), is a member of the cadherin family of cell adhesion molecules. Cadherins are calcium-dependent transmembrane proteins which bind to one another in a homophilic manner. On their cytoplasmic side, they associate with the three catenins, alpha, beta, and gamma (plakoglobin). This association links the cadherin protein to the cytoskeleton. Without association with the catenins, the cadherins are non-adhesive. Cadherins play a role in development, specifically in tissue formation. They may also help to maintain tissue architecture in the adult. VE-cadherin has been shown to play important roles in vasculogenesis and angiogenesis. VE-cadherin is a classical cadherin molecule. Classical cadherins consist of a large extracellular domain which contains DXD and DXNDN repeats responsible for mediating calcium-dependent adhesion, a single-pass transmembrane domain, and a short carboxy-terminal cytoplasmic domain responsible for interacting with the catenins. Human VE-cadherin is a 784 amino acid (aa) residue protein with a 25 aa signal sequence and a 759 aa propeptide. The mature protein begins at amino acid 48 and has a 546 aa extracellular domain, a 27 aa transmembrane domain, and a 164 aa cytoplasmic domain. The human and mouse mature VE-cadherin proteins share approximately 74 % homology.,Cadherin-5
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分子量
- observerd band 130kDa
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基因ID
- 1003
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UniProt
- P33151
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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