C1R 抗体 (Cleaved-Arg463)
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北京 101111
Quick Overview for C1R 抗体 (Cleaved-Arg463) (ABIN7224738)
抗原
See all C1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-470, Cleaved-Arg463
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原理
- Rabbit Anti-Cleaved-C1r HC (R463) Polyclonal Antibody
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特异性
- Cleaved-C1r HC (R463) Polyclonal Antibody detects endogenous levels of fragment of activated C1r HC protein resulting from cleavage adjacent to R463.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human C1r HC at AA range: 390-470
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亚型
- IgG
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anti-Complement Component 1, R Subcomponent (C1R) (AA 65-192) antibody
C1R 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, R Subcomponent (C1R) antibodyC1R 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, R Subcomponent (C1R) (AA 466-705) antibodyC1R 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, R Subcomponent (C1R) (AA 1-705) antibodyC1R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, R Subcomponent (C1R) (AA 231-430) antibodyC1R 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, R Subcomponent (C1R) (AA 262-562) antibodyC1R 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Complement Component 1, R Subcomponent (C1R) (AA 445-494), (Cleaved-Ile464) antibodyC1R 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, R Subcomponent (C1R) (cleaved), (Internal Region) antibodyC1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, R Subcomponent (C1R) (AA 1-705) antibodyC1R 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- C1R (Complement Component 1, R Subcomponent (C1R))
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别名
- C1r HC
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背景
- C1R, Complement C1r subcomponent, Complement component 1 subcomponent rThe first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full-length C1r chain and the cleaved B chain.
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分子量
- 51kD
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基因ID
- 715
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UniProt
- P00736
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途径
- Complement System
抗原
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