CSK 抗体
Quick Overview for CSK 抗体 (ABIN7214352)
抗原
See all CSK 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Csk Polyclonal Antibody
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特异性
- Csk Polyclonal Antibody detects endogenous levels of Csk protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Csk around the non-phosphorylation site of S364
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亚型
- IgG
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anti-C-Src tyrosine Kinase (CSK) (AA 1-100) antibody
CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyCSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (C-Term) antibodyVerified CSK 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyCSK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5F3 unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyKD Validated CSK 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB1920 unconjugated Recombinant Antibody
anti-C-Src tyrosine Kinase (CSK) (AA 243-438) antibodyCSK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibodyCSK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 1-200) antibodyCSK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 325-416) antibodyCSK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 67-101), (N-Term) antibodyCSK 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50568 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CSK (C-Src tyrosine Kinase (CSK))
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别名
- Csk
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背景
- Rabbit Anti-Csk Polyclonal Antibody,CSK, Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL,All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine, however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src-related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as carboxy terminal regulatory sequences. Csk phosphorylates Src on Y527 and also downregulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy terminal regulatory sites.,Tyrosine-protein kinase CSK
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分子量
- observerd band 50kDa
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基因ID
- 1445
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UniProt
- P41240
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途径
- TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
抗原
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