BCAR3 抗体 (AA 730-810)
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Quick Overview for BCAR3 抗体 (AA 730-810) (ABIN7225364)
抗原
See all BCAR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 730-810
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原理
- BCAR3 Polyclonal Antibody
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特异性
- BCAR3 Polyclonal Antibody detects endogenous levels of BCAR3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human BCAR3 at AA range: 730-810
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
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别名
- BCAR3
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背景
- Rabbit Anti-BCAR3 Polyclonal Antibody,BCAR3, NSP2, SH2D3B, Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B,Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. BCAR3 (breast cancer anti-estrogen resistance 3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for BCAR3.,Breast cancer anti-estrogen resistance protein 3
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基因ID
- 8412
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UniProt
- O75815
抗原
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