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BCAR3 抗体 (AA 730-810)

This 兔 多克隆 anti-BCAR3 antibody specifically detects BCAR3 in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7225364
发货至: 中国
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Quick Overview for BCAR3 抗体 (AA 730-810) (ABIN7225364)

抗原

See all BCAR3 抗体
BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

适用

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宿主

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克隆类型

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多克隆

标记

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This BCAR3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 730-810

    原理

    BCAR3 Polyclonal Antibody

    特异性

    BCAR3 Polyclonal Antibody detects endogenous levels of BCAR3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human BCAR3 at AA range: 730-810

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

    别名

    BCAR3

    背景

    Rabbit Anti-BCAR3 Polyclonal Antibody,BCAR3, NSP2, SH2D3B, Breast cancer anti-estrogen resistance protein 3, Novel SH2-containing protein 2, SH2 domain-containing protein 3B,Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. BCAR3 (breast cancer anti-estrogen resistance 3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for BCAR3.,Breast cancer anti-estrogen resistance protein 3

    基因ID

    8412

    UniProt

    O75815
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