BDKRB1 抗体 (AA 180-260)
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Quick Overview for BDKRB1 抗体 (AA 180-260) (ABIN7224134)
抗原
See all BDKRB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 180-260
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原理
- Bradykinin B1 R Polyclonal Antibody
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特异性
- Bradykinin B1 R Polyclonal Antibody detects endogenous levels of Bradykinin B1 R protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Bradykinin B1 R at AA range: 180-260
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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别名
- Bradykinin B1 R
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背景
- Rabbit Anti-Bradykinin B1 R Polyclonal Antibody,BDKRB1, BRADYB1, B1 bradykinin receptor, B1R, BK-1 receptor,Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by BDKRB1 (bradykinin receptor B1) is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for BDKRB1.,B1 bradykinin receptor
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分子量
- observerd band 40kDa
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基因ID
- 623
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UniProt
- P46663
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途径
- ACE Inhibitor Pathway
抗原
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