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BACE1 抗体

This anti-BACE1 antibody is a 兔 多克隆 antibody detecting BACE1 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7227450
发货至: 中国

Quick Overview for BACE1 抗体 (ABIN7227450)

抗原

See all BACE1 抗体
BACE1 (Beta-secretase 1 (BACE1))

适用

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人, 小鼠, 大鼠

宿主

  • 86
  • 12
  • 2
  • 1
  • 1

克隆类型

  • 71
  • 31
多克隆

标记

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This BACE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    BACE Polyclonal Antibody

    特异性

    This antibody detects endogenous levels of BACE.

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human BACE protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    BACE1 (Beta-secretase 1 (BACE1))

    别名

    BACE

    背景

    Rabbit Anti-BACE Polyclonal Antibody,Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2,BACE1 (Beta-Secretase 1) is a Protein Coding gene. Diseases associated with BACE1 include Nervous System Disease and Alzheimer Disease. Among its related pathways are Alzheimers Disease Pathway and A-beta Pathways: plaque Formation and APP Metabolism. BACE1 encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.,BACE

    基因ID

    23621

    UniProt

    P56817
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