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BAG4 抗体 (C-Term)

This 兔 多克隆 anti-BAG4 antibody specifically detects BAG4 in WB, ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7213758
发货至: 中国
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Quick Overview for BAG4 抗体 (C-Term) (ABIN7213758)

抗原

See all BAG4 抗体
BAG4 (BCL2-Associated Athanogene 4 (BAG4))

适用

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人, 小鼠, 大鼠

宿主

  • 54
  • 4
  • 3
  • 1

克隆类型

  • 52
  • 10
多克隆

标记

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This BAG4 antibody is un-conjugated

应用范围

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  • 4
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 9
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    C-Term

    原理

    Bag-4 Polyclonal Antibody

    特异性

    Bag-4 Polyclonal Antibody detects endogenous levels of Bag-4 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Bag-4

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    BAG4 (BCL2-Associated Athanogene 4 (BAG4))

    别名

    Bag-4

    背景

    Rabbit Anti-Bag-4 Polyclonal Antibody,BAG4, SODD, BAG family molecular chaperone regulator 4, BAG-4, Bcl-2-associated athanogene 4, Silencer of death domains,The protein encoded by BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein (BCL2 associated athanogene 4) was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.,BAG family molecular chaperone regulator 4

    基因ID

    9530

    UniProt

    O95429

    途径

    Regulation of Actin Filament Polymerization
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