AATK 抗体 (AA 1110-1190)
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北京 101111
Quick Overview for AATK 抗体 (AA 1110-1190) (ABIN7229418)
抗原
See all AATK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1110-1190
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原理
- Rabbit Anti-LMTK1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of LMTK1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human LMTK1 protein at AA range: 1110-1190
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- AATK (Apoptosis-Associated tyrosine Kinase (AATK))
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别名
- LMTK1
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背景
- Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BPThe protein encoded by AATK contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of AATK may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. AATK has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for AATK.
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分子量
- 151kD
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基因ID
- 9625
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UniProt
- Q6ZMQ8
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途径
- RTK signaling, Regulation of Cell Size
抗原
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