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AMACR 抗体

This 小鼠 单克隆 anti-AMACR antibody specifically detects AMACR in WB, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7201086
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for AMACR 抗体 (ABIN7201086)

抗原

See all AMACR 抗体
AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

适用

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人, 小鼠, 大鼠

宿主

  • 88
  • 56
  • 2
小鼠

克隆类型

  • 91
  • 55
单克隆

标记

  • 69
  • 11
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  • 6
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  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This AMACR antibody is un-conjugated

应用范围

  • 102
  • 85
  • 37
  • 35
  • 34
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  • 12
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  • 8
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  • 5
  • 2
  • 1
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    AMACR Monoclonal Antibody

    特异性

    The antibody detects endogenous AMCAR/P504S proteins.

    纯化方法

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

    免疫原

    Synthetic Peptide

    亚型

    IgG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000), IF (1:200), IHC-P (1:200).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

    别名

    AMACR

    背景

    Mouse Anti-AMACR Monoclonal Antibody,AMACR, Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase,AMACR encodes a racemase. Alpha-methylacyl-CoA racemase interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Alpha-methylacyl-CoA racemase from this locus localize to both mitochondria and peroxisomes. Mutations in AMACR may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between AMACR and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.,Alpha-methylacyl-CoA racemase

    基因ID

    23600

    UniProt

    Q9UHK6

    途径

    Monocarboxylic Acid Catabolic Process
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