alpha Actinin 抗体
The 小鼠 单克隆 anti-alpha Actinin antibody is suitable to detect alpha Actinin in samples from 人, 小鼠 和 大鼠. It has been validated for IHC (p).
产品编号 ABIN7212180
发货至:
中国
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Quick Overview for alpha Actinin 抗体 (ABIN7212180)
抗原
See all alpha Actinin (ACTN) 抗体
alpha Actinin (ACTN)
(alpha-Actinin Skeletal Muscle (ACTN))
适用
人, 小鼠, 大鼠
宿主
小鼠
克隆类型
单克隆
标记
This alpha Actinin antibody is un-conjugated
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
克隆位点
4A12
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原理
- a-actinin Monoclonal Antibody (4A12)
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特异性
- A-actinin Monoclonal Antibody(4A12) detects endogenous levels of ACTN1.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
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免疫原
- Recombinant Protein of a-actinin of ACTN1
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亚型
- IgG1
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anti-alpha-Actinin Skeletal Muscle (ACTN) antibody
ACTN 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-Actinin Skeletal Muscle (ACTN) antibodyACTN 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal CB11 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
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别名
- a-actinin
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背景
- Mouse Anti-a-actinin Monoclonal Antibody (4A12),ACTN1,Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 (actinin alpha 1) encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for ACTN1.,ACTN1
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基因ID
- 87
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UniProt
- P12814
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途径
- Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
抗原
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