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AKR1C2 抗体 (AA 40-120)

The 兔 多克隆 anti-AKR1C2 antibody is suitable to detect AKR1C2 in samples from 人. It has been validated for WB, ELISA 和 IHC (p).
产品编号 ABIN7219996
发货至: 中国
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Quick Overview for AKR1C2 抗体 (AA 40-120) (ABIN7219996)

抗原

See all AKR1C2 抗体
AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

适用

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宿主

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克隆类型

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多克隆

标记

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This AKR1C2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 40-120

    原理

    DD2 Polyclonal Antibody

    特异性

    DD2 Polyclonal Antibody detects endogenous levels of DD2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human DD2 at AA range: 40-120

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

    别名

    DD2

    背景

    Rabbit Anti-DD2 Polyclonal Antibody,AKR1C2, DDH2, Aldo-keto reductase family 1 member C2, 3-alpha-HSD3, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, DD-2, DD2, Dihydrodiol dehydrogenase/bile acid-binding protein, DD/BABP, Trans-1, 2-dihydrobenzene-1,2-diol,AKR1C2 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. AKR1C2 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.,Aldo-keto reductase family 1 member C2

    分子量

    observerd band 37kDa

    基因ID

    1646

    UniProt

    P52895

    途径

    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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