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AGRN 抗体 (AA 1900-1980)

This anti-AGRN antibody is a 兔 多克隆 antibody detecting AGRN in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7227240
发货至: 中国

Quick Overview for AGRN 抗体 (AA 1900-1980) (ABIN7227240)

抗原

See all AGRN 抗体
AGRN (Agrin (AGRN))

适用

人, 大鼠, 小鼠

宿主

  • 22
  • 5

克隆类型

  • 22
  • 5
多克隆

标记

  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AGRN antibody is un-conjugated

应用范围

  • 14
  • 10
  • 9
  • 8
  • 5
  • 4
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1900-1980

    原理

    AGRIN Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of AGRIN protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human AGRIN protein at AA range: 1900-1980

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    AGRN (Agrin (AGRN))

    别名

    AGRIN

    背景

    Rabbit Anti-AGRIN Polyclonal Antibody,Agrin, Agrin N-terminal 110 kDa subunit, Agrin C-terminal 110 kDa subunit, Agrin C-terminal 90 kDa fragment, C90, Agrin C-terminal 22 kDa fragment, C22,AGRN encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in AGRN was found. Alternative splicing results in multiple transcript variants encoding different isoforms.,AGRIN

    基因ID

    375790

    UniProt

    O00468

    途径

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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