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alpha Adducin 抗体 (pThr445)

This 兔 多克隆 anti-alpha Adducin antibody specifically detects alpha Adducin in ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7219384
发货至: 中国
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Quick Overview for alpha Adducin 抗体 (pThr445) (ABIN7219384)

抗原

See all alpha Adducin (ADD1) 抗体
alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

适用

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人, 小鼠, 大鼠

宿主

  • 90
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克隆类型

  • 89
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多克隆

标记

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This alpha Adducin antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 17
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    pThr445

    原理

    Adducin α (phospho Thr445) Polyclonal Antibody

    特异性

    Phospho-Adducin α (T445) Polyclonal Antibody detects endogenous levels of Adducin α protein only when phosphorylated at T445.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human Adducin alpha Phospho-Thr445

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

    别名

    Adducin alpha

    背景

    Rabbit Anti-Adducin α (phospho Thr445) Polyclonal Antibody,ADD1, ADDA, Alpha-adducin, Erythrocyte adducin subunit alpha,Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.,Alpha-adducin

    基因ID

    118

    UniProt

    P35611

    途径

    Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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