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ATF6B 抗体 (AA 370-450)

This 兔 多克隆 anti-ATF6B antibody specifically detects ATF6B in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7213716
发货至: 中国
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Quick Overview for ATF6B 抗体 (AA 370-450) (ABIN7213716)

抗原

See all ATF6B 抗体
ATF6B (Activating Transcription Factor 6 beta (ATF6B))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATF6B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 370-450

    原理

    ATF-6β Polyclonal Antibody

    特异性

    ATF-6β Polyclonal Antibody detects endogenous levels of ATF-6β protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human ATF-6beta at AA range: 370-450

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ATF6B (Activating Transcription Factor 6 beta (ATF6B))

    别名

    ATF-6beta

    背景

    Rabbit Anti-ATF-6β Polyclonal Antibody,ATF6B, CREBL1, G13, Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein,The protein (activating transcription factor 6 beta) encoded by ATF6B is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for ATF6B.,Cyclic AMP-dependent transcription factor ATF-6 beta

    基因ID

    1388

    UniProt

    Q99941

    途径

    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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