ATF6B 抗体 (AA 370-450)
Our Local Distributor
北京 101111
Quick Overview for ATF6B 抗体 (AA 370-450) (ABIN7213716)
抗原
See all ATF6B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 370-450
-
原理
- ATF-6β Polyclonal Antibody
-
特异性
- ATF-6β Polyclonal Antibody detects endogenous levels of ATF-6β protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the Internal region of human ATF-6beta at AA range: 370-450
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- ATF6B (Activating Transcription Factor 6 beta (ATF6B))
-
别名
- ATF-6beta
-
背景
- Rabbit Anti-ATF-6β Polyclonal Antibody,ATF6B, CREBL1, G13, Cyclic AMP-dependent transcription factor ATF-6 beta, cAMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, ATF6-beta, Protein G13, cAMP response element-binding protein-related protein,The protein (activating transcription factor 6 beta) encoded by ATF6B is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for ATF6B.,Cyclic AMP-dependent transcription factor ATF-6 beta
-
基因ID
- 1388
-
UniProt
- Q99941
-
途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
抗原
-