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ATF6B 抗体 (C-Term)

Cited in 1 publication. The 兔 多克隆 anti-ATF6B antibody (Clone RB25603) (ABIN651294) specifically detects ATF6B in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 Hamster samples.
产品编号 ABIN651294
发货至: 中国
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Quick Overview for ATF6B 抗体 (C-Term) (ABIN651294)

抗原

See all ATF6B 抗体
ATF6B (Activating Transcription Factor 6 beta (ATF6B))

适用

  • 45
  • 14
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, Hamster

宿主

  • 44
  • 1
兔

克隆类型

  • 44
  • 1
多克隆

标记

  • 19
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This ATF6B antibody is un-conjugated

应用范围

  • 36
  • 15
  • 13
  • 13
  • 8
  • 6
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB25603
  • 抗原表位

    • 15
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 560-589, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CREBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-589 amino acids from the C-terminal region of human CREBL1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • So, Chen, Wang, Wu, Huang, Lai, Pan, Kang, Huang: "Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells." in: OncoTargets and therapy, Vol. 9, pp. 2519-33, (2016) (PubMed).

  • 抗原

    ATF6B (Activating Transcription Factor 6 beta (ATF6B))

    别名

    CREBL1

    背景

    CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum, however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus.

    分子量

    76709

    基因ID

    1388

    NCBI登录号

    NP_001129625, NP_004372

    UniProt

    Q99941

    途径

    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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