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ACTN2/3 抗体 (AA 1-80)

This 兔 多克隆 anti-ACTN2/3 antibody specifically detects ACTN2/3 in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7213470
发货至: 中国
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Quick Overview for ACTN2/3 抗体 (AA 1-80) (ABIN7213470)

抗原

See all ACTN2/3 抗体
ACTN2/3 (Actinin, alpha 2/3 (ACTN2/3))

适用

人, 小鼠, 大鼠

宿主

  • 3

克隆类型

  • 3
多克隆

标记

  • 3
This ACTN2/3 antibody is un-conjugated

应用范围

  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 1
    • 1
    • 1
    AA 1-80

    原理

    Actinin-α2/3 Polyclonal Antibody

    特异性

    Actinin-α2/3 Polyclonal Antibody detects endogenous levels of Actinin-α2/3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human Actinin-alpha2/3 at AA range: 1-80

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ACTN2/3 (Actinin, alpha 2/3 (ACTN2/3))

    别名

    Actinin-alpha2/3

    背景

    Rabbit Anti-Actinin-α2/3 Polyclonal Antibody,ACTN2, Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein, ACTN3, Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein,Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN2 encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for ACTN2.,Alpha-actinin-2

    基因ID

    88, 89
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