ACTN2/3 抗体 (AA 31-80)
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北京 101111
Quick Overview for ACTN2/3 抗体 (AA 31-80) (ABIN1533709)
抗原
See all ACTN2/3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-80
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原理
- Actinin-α2/3 Antibody
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特异性
- Actinin-α2/3 Polyclonal Antibody detects endogenous levels of Actinin-α2/3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Actinin alpha-2/3. AA range:31-80
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亚型
- IgG
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anti-Actinin, alpha 2/3 (ACTN2/3) (N-Term) antibody
ACTN2/3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2/3 (ACTN2/3) (N-Term) antibodyACTN2/3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ACTN2/3 (Actinin, alpha 2/3 (ACTN2/3))
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背景
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Synonyms: ACTN2, Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein, ACTN3, Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein
Background: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],
Gene Name: ACTN2/ACTN3
Protein Name: Alpha-actinin-2/3
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分子量
- 103 kDa
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基因ID
- 88, 89
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OMIM
- 102573
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UniProt
- P35609
抗原
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