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ACTN1 抗体 (AA 1-80)

The 兔 多克隆 anti-ACTN1 antibody is suitable to detect ACTN1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7225622
发货至: 中国
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Quick Overview for ACTN1 抗体 (AA 1-80) (ABIN7225622)

抗原

See all ACTN1 抗体
ACTN1 (Actinin, alpha 1 (ACTN1))

适用

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人, 小鼠, 大鼠

宿主

  • 49
  • 12
  • 1

克隆类型

  • 50
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多克隆

标记

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This ACTN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 1-80

    原理

    Actinin-α1 Polyclonal Antibody

    特异性

    Actinin-α1 Polyclonal Antibody detects endogenous levels of Actinin-α1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human Actinin-alpha1 at AA range: 1-80

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    ACTN1 (Actinin, alpha 1 (ACTN1))

    别名

    Actinin-alpha1

    背景

    Rabbit Anti-Actinin-α1 Polyclonal Antibody,ACTN1, Alpha-actinin-1, Alpha-actinin cytoskeletal isoform, F-actin cross-linking protein, Non-muscle alpha-actinin-1,Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. ACTN1 (actinin alpha 1) encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for ACTN1.,Alpha-actinin-1

    基因ID

    87

    UniProt

    P12814

    途径

    Cell-Cell Junction Organization
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