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AKAP12 抗体 (AA 270-350)

This 兔 多克隆 anti-AKAP12 antibody specifically detects AKAP12 in ELISA, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7226038
发货至: 中国
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Quick Overview for AKAP12 抗体 (AA 270-350) (ABIN7226038)

抗原

See all AKAP12 抗体
AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

适用

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宿主

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克隆类型

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多克隆

标记

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This AKAP12 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 270-350

    原理

    AKAP 250 Polyclonal Antibody

    特异性

    AKAP 250 Polyclonal Antibody detects endogenous levels of AKAP 250 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human AKAP 250 at AA range: 270-350

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))

    别名

    AKAP 250

    背景

    Rabbit Anti-AKAP 250 Polyclonal Antibody,AKAP12, AKAP250, A-kinase anchor protein 12, AKAP-12, A-kinase anchor protein 250 kDa, AKAP 250, Gravin, Myasthenia gravis autoantigen,The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP12 (A-kinase anchoring protein 12) encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.,A-kinase anchor protein 12

    基因ID

    9590

    UniProt

    Q02952

    途径

    cAMP Metabolic Process
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