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HTR2C 抗体 (AA 130-210)

This 兔 多克隆 antibody specifically detects HTR2C in WB, ELISA, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7221618
发货至: 中国
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Quick Overview for HTR2C 抗体 (AA 130-210) (ABIN7221618)

抗原

See all HTR2C 抗体
HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

适用

  • 71
  • 48
  • 43
  • 7
  • 6
  • 4
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 68
  • 3
  • 1

克隆类型

  • 60
  • 12
多克隆

标记

  • 34
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HTR2C antibody is un-conjugated

应用范围

  • 54
  • 25
  • 13
  • 13
  • 13
  • 9
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 130-210

    原理

    SR-2C Polyclonal Antibody

    特异性

    SR-2C Polyclonal Antibody detects endogenous levels of SR-2C protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human SR-2C at AA range: 130-210

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

    别名

    SR-2C

    背景

    Rabbit Anti-SR-2C Polyclonal Antibody,HTR2C, HTR1C, 5-hydroxytryptamine receptor 2C, 5-HT-2C, 5-HT2C, 5-HTR2C, 5-hydroxytryptamine receptor 1C, 5-HT-1C, 5-HT1C, Serotonin receptor 2C,HTR2C encodes a seven-transmembrane G-protein-coupled receptor. The 5-hydroxytryptamine receptor 2C responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.,5-hydroxytryptamine receptor 2C

    分子量

    observerd band 55kDa

    基因ID

    3358

    UniProt

    P28335

    途径

    Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
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