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HAAO 抗体 (AA 30-110)

This 兔 多克隆 anti-HAAO antibody specifically detects HAAO in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7227096
发货至: 中国
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Quick Overview for HAAO 抗体 (AA 30-110) (ABIN7227096)

抗原

See all HAAO 抗体
HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

适用

  • 20
  • 13
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 27
  • 1

克隆类型

  • 27
  • 1
多克隆

标记

  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HAAO antibody is un-conjugated

应用范围

  • 23
  • 13
  • 13
  • 11
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-110

    原理

    3HAO Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of 3HAO protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human 3HAO protein at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

    别名

    3HAO

    背景

    Rabbit Anti-3HAO Polyclonal Antibody,3-hydroxyanthranilate 3,4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, 3-hydroxyanthranilic acid dioxygenase, HAD,HAAO (3-Hydroxyanthranilate 3,4-Dioxygenase) is a Protein Coding gene. Among its related pathways are Metabolism and superpathway of tryptophan utilization. 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.,3HAO

    基因ID

    23498

    UniProt

    P46952
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