Integrin beta 7 抗体 (AA 20-174)
Quick Overview for Integrin beta 7 抗体 (AA 20-174) (ABIN7193968)
抗原
See all Integrin beta 7 (ITGB7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 20-174
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原理
- ITGB7 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human ITGB7 (AA: 20-174) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Integrin beta 7 (ITGB7)
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别名
- ITGB7
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背景
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This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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分子量
- 86.9 kDa
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基因ID
- 3695
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UniProt
- P26010
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途径
- Integrin Complex
抗原
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