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HLA-F 抗体 (AA 22-305)

HLAF 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3F11F4 unconjugated
产品编号 ABIN7193964
发货至: 中国
  • 抗原 See all HLA-F (HLAF) 抗体
    HLA-F (HLAF) (HLA Class I alpha F (HLAF))
    抗原表位
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 22-305
    适用
    • 17
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 15
    • 2
    小鼠
    克隆类型
    • 14
    • 3
    单克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    This HLA-F antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 4
    • 4
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    HLA-F Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. Coli.
    克隆位点
    3F11F4
    亚型
    IgG2b
    Top Product
    Discover our top product HLAF Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    HLA-F (HLAF) (HLA Class I alpha F (HLAF))
    别名
    HLA-F (HLAF 产品)
    背景

    This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.

    分子量
    39 kDa
    基因ID
    3134
    UniProt
    P30511
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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