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HLA-F 抗体 (AA 22-305)

This anti-HLA-F antibody is a 小鼠 单克隆 antibody detecting HLA-F in WB, ELISA 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN7193964
发货至: 中国

Quick Overview for HLA-F 抗体 (AA 22-305) (ABIN7193964)

抗原

See all HLA-F (HLAF) 抗体
HLA-F (HLAF) (HLA Class I alpha F (HLAF))

适用

  • 17
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 15
  • 2
小鼠

克隆类型

  • 14
  • 3
单克隆

标记

  • 13
  • 1
  • 1
  • 1
  • 1
This HLA-F antibody is un-conjugated

应用范围

  • 12
  • 6
  • 4
  • 4
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)

克隆位点

3F11F4
  • 抗原表位

    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 22-305

    原理

    HLA-F Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    HLA-F (HLAF) (HLA Class I alpha F (HLAF))

    别名

    HLA-F

    背景

    This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.

    分子量

    39 kDa

    基因ID

    3134

    UniProt

    P30511

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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