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CD11b 抗体 (AA 623-728)

This anti-CD11b antibody is a 小鼠 单克隆 antibody detecting CD11b in FACS, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7193892
发货至: 中国

Quick Overview for CD11b 抗体 (AA 623-728) (ABIN7193892)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD11b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA

克隆位点

3A4B10
  • 抗原表位

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    AA 623-728

    原理

    ITGAM Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    ITGAM

    背景

    This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

    分子量

    127.1 kDa

    基因ID

    3684

    UniProt

    P11215

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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