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Perforin 1 抗体 (AA 148-372)

PRF1 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8A8C10 unconjugated
产品编号 ABIN7193869
发货至: 中国
  • 抗原 See all Perforin 1 (PRF1) 抗体
    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
    抗原表位
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 148-372
    适用
    • 78
    • 25
    • 10
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 57
    • 39
    • 4
    小鼠
    克隆类型
    • 58
    • 42
    单克隆
    标记
    • 56
    • 13
    • 11
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Perforin 1 antibody is un-conjugated
    应用范围
    • 49
    • 39
    • 29
    • 19
    • 15
    • 10
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human PRF1 (AA: extra 148-372) expressed in E. coli.
    克隆位点
    8A8C10
    亚型
    IgG1
    Top Product
    Discover our top product PRF1 Primary Antibody
  • 应用备注
    WB:1:500 - 1:2000, IHC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,
    限制
    仅限研究用
  • 缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • 抗原
    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
    别名
    PRF1 (PRF1 产品)
    别名
    FLH2 antibody, HPLH2 antibody, P1 antibody, PFN1 antibody, PFP antibody, PRF1 antibody, Pfn antibody, Pfp antibody, Prf-1 antibody, Cyta antibody, RATCYTA antibody, LOC443187 antibody, perforin antibody, prf1 antibody, cytolysin antibody, perforin-1 antibody, perforin-1-like antibody, perforin 1 antibody, perforin 1 (pore forming protein) antibody, perforin antibody, perforin 1 L homeolog antibody, PRF1 antibody, Prf1 antibody, LOC443187 antibody, prf1 antibody, prf1.L antibody
    背景

    Description: This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood.

    Aliases: P1, PFP, HPLH2

    分子量
    61.3 kDa
    基因ID
    5551
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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