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Perforin 1 抗体 (AA 148-372)

This anti-Perforin 1 antibody is a 小鼠 单克隆 antibody detecting Perforin 1 in WB, IHC, ELISA 和 FACS. Suitable for 人 和 小鼠.
产品编号 ABIN7193869
发货至: 中国

Quick Overview for Perforin 1 抗体 (AA 148-372) (ABIN7193869)

抗原

See all Perforin 1 (PRF1) 抗体
Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

适用

  • 99
  • 25
  • 8
  • 7
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 61
  • 56
  • 4
小鼠

克隆类型

  • 64
  • 57
单克隆

标记

  • 60
  • 14
  • 13
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Perforin 1 antibody is un-conjugated

应用范围

  • 48
  • 46
  • 37
  • 18
  • 17
  • 13
  • 10
  • 7
  • 7
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

8A8C10
  • 抗原表位

    • 25
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 148-372

    原理

    PRF1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human PRF1 (AA: 148-372) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

    别名

    PRF1

    背景

    This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood.

    分子量

    61.3 kDa

    基因ID

    5551

    UniProt

    P14222

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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