IKZF1 抗体 (AA 401-520)
Quick Overview for IKZF1 抗体 (AA 401-520) (ABIN7193822)
抗原
See all IKZF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 401-520
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原理
- IKZF1 Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human IKZF1 (AA: 401-520) expressed in E. Coli.
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亚型
- IgG2b
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anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-265) antibody
IKZF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-270) antibodyIKZF1 适用: 人 WB, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 415-444), (C-Term) antibodyIKZF1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24656 unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (C-Term) antibody (PE)IKZF1 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal 4E9 PE
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) antibodyIKZF1 适用: 人 WB, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 428-459), (C-Term) antibodyIKZF1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (Middle Region) antibodyIKZF1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (Internal Region) antibodyVerified IKZF1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (AA 1-477) antibodyIKZF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1) (N-Term) antibodyIKZF1 适用: 小鼠 WB, ChIP, ChIP-seq 宿主: 小鼠 Monoclonal 2A9 unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))
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别名
- IKZF1
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背景
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This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence, resulting in members with and without DNA-binding properties. Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and are thought to function as dominant-negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL).
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分子量
- 57.5 kDa
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UniProt
- Q13422
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途径
- Production of Molecular Mediator of Immune Response
抗原
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