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NUP98 抗体 (AA 1-218)

This anti-NUP98 antibody is a 小鼠 单克隆 antibody detecting NUP98 in WB, ELISA, ICC 和 FACS. Suitable for 人 和 猴.
产品编号 ABIN7193802
发货至: 中国

Quick Overview for NUP98 抗体 (AA 1-218) (ABIN7193802)

抗原

See all NUP98 抗体
NUP98 (Nucleoporin 98kDa (NUP98))

适用

  • 54
  • 20
  • 15
  • 8
  • 6
  • 6
  • 6
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  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 猴

宿主

  • 45
  • 11
  • 1
小鼠

克隆类型

  • 42
  • 15
单克隆

标记

  • 47
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NUP98 antibody is un-conjugated

应用范围

  • 44
  • 18
  • 17
  • 14
  • 8
  • 7
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

3G8C7
  • 抗原表位

    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-218

    原理

    NUP98 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human NUP98 (AA: 1-218) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原

    NUP98 (Nucleoporin 98kDa (NUP98))

    别名

    NUP98

    背景

    Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin.

    分子量

    197.5 kDa

    基因ID

    4928

    UniProt

    P52948

    途径

    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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