CD3D 抗体 (AA 127-171)
Quick Overview for CD3D 抗体 (AA 127-171) (ABIN7193637)
抗原
See all CD3D 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 127-171
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原理
- CD3D Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD3D (AA: 127-171) expressed in E. Coli.
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亚型
- IgG2b
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应用备注
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ELISA: 1/10000
FCM: 1/200-1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
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别名
- CD3D
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背景
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The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
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分子量
- 18.9 kDa
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基因ID
- 915
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UniProt
- P04234
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途径
- TCR Signaling, CXCR4-mediated Signaling Events
抗原
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