PD-1 抗体 (AA 192-288)
Quick Overview for PD-1 抗体 (AA 192-288) (ABIN7193524)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - AA 192-288
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原理
 - PD1 Antibody
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纯化方法
 - Purified antibody
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免疫原
 - Purified recombinant fragment of human PD1 (AA: 192-288) expressed in E. Coli.
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亚型
 - IgG1
 
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - Purified antibody in PBS with 0.05 % sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
 - PD1
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背景
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This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
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分子量
 - 31.6 kDa
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基因ID
 - 5133
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UniProt
 - Q15116
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途径
 - Cancer Immune Checkpoints
 
抗原
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